中文名稱：兔抗STAT2 (phospho-Tyr690)多克隆抗體

英文名稱： Anti-STAT2 (phospho-Tyr690) rabbit polyclonal antibody

別名： P113; ISGF-3; STAT113

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）避光

宿主： Rabbit

抗原： STAT2 (phospho-Tyr690)

反應(yīng)種屬： Human, Rat

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

STAT2 (phospho-Tyr690)

Immunogen:

Synthetic peptide of human STAT2 (phospho-Tyr690)

Full name:

signal transducer and activator of transcription 2, 113kDa (phospho-Tyr690)

Synonyms：

P113; ISGF-3; STAT113

SwissProt:

P52630

WB Predicted band size:

98 kDa

WB Positive control:

Hela cells treated with IFN-α

WB Recommended dilution:

500-1000

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兔抗STAT2 (phospho-Tyr690)多克隆抗體

Background:	The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:	WB
Name of antibody:	STAT2 (phospho-Tyr690)
Immunogen:	Synthetic peptide of human STAT2 (phospho-Tyr690)
Full name:	signal transducer and activator of transcription 2, 113kDa (phospho-Tyr690)
Synonyms：	P113; ISGF-3; STAT113
SwissProt:	P52630
WB Predicted band size:	98 kDa
WB Positive control:	Hela cells treated with IFN-α
WB Recommended dilution:	500-1000