Background: |
This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
STAM |
Immunogen: |
Fusion protein of human STAM |
Full name: |
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
Synonyms: |
STAM1; STAM-1 |
SwissProt: |
Q92783 |
IHC positive control: |
Human gastric cancer and human esophagus cancer |
IHC Recommend dilution: |
50-200 |