Background: |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SRC |
Immunogen: |
Fusion protein of human SRC |
Full name: |
V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
Synonyms: |
ASV; SRC1; c-SRC; p60-Src |
SwissProt: |
P12931 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human lymphoma and Human colon cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
60 kDa |
WB Positive control: |
PC3 cells |
WB Recommended dilution: |
200-1000 |