Background: |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
Applications: |
WB |
Name of antibody: |
SRC(Phospho-Ser75) |
Immunogen: |
Peptide sequence around phosphorylation site of serine 75 (V-T-S(p)-P-Q) derived from Human Src. |
Full name: |
SRC proto-oncogene, non-receptor tyrosine kinase |
Synonyms: |
ASV; SRC1; c-SRC; p60-Src |
SwissProt: |
P12931 |
WB Predicted band size: |
60 kDa |
WB Positive control: |
COLO205lysates |
WB Recommended dilution: |
500-1000 |