Background: |
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SPR |
Immunogen: |
Synthetic peptide of human SPR |
Full name: |
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
Synonyms: |
SDR38C1 |
SwissProt: |
P35270 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human breast cancer and Human thyroid cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
28 kDa |
WB Positive control: |
Human chromaffin cells tumor tissue and lovo cells |
WB Recommended dilution: |
500-2000 |