中文名稱：兔抗SPIN2B多克隆抗體

英文名稱： Anti-SPIN2B rabbit polyclonal antibody

別名： SPIN-2; dJ323P24.2; SPIN2_duplicate

抗原： SPIN2B

儲存： 冷凍（-20℃）

宿主： Rabbit

相關(guān)類別：一抗

反應(yīng)種屬： Human

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.

Applications:

ELISA, IHC

Name of antibody:

SPIN2B

Immunogen:

Full length fusion protein

Full name:

Spindlin family, member 2B

Synonyms：

SPIN-2; dJ323P24.2; SPIN2_duplicate

SwissProt:

Q9BPZ2

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

25-100

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兔抗SPIN2B多克隆抗體

Background:	Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.
Applications:	ELISA, IHC
Name of antibody:	SPIN2B
Immunogen:	Full length fusion protein
Full name:	Spindlin family, member 2B
Synonyms：	SPIN-2; dJ323P24.2; SPIN2_duplicate
SwissProt:	Q9BPZ2
IHC positive control:	Human cervical cancer
IHC Recommend dilution:	25-100