中文名稱：兔抗SPATA19多克隆抗體

英文名稱： Anti-SPATA19 rabbit polyclonal antibody

別名： spermatogenesis associated 19 CT132; SPAS1; spergen1

抗原： SPATA19

儲存： 冷凍（-20℃）

宿主： Rabbit

相關(guān)類別：一抗

反應(yīng)種屬： Human

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

ackground:

SPATA19(spermatogenesis associated 19), also known as spergen1 (spermatogenic cell-specific gene 1 protein), CT132 or SPAS1, is a 167 amino acid mitochondrial outer membrane protein suggested to function in spermiogenesis. Expressed specifically in testis, SPATA19 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxiatelangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms’ tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Applications:

ELISA, IHC

Name of antibody:

SPATA19

Immunogen:

Fusion protein of human SPATA19

Full name:

spermatogenesis associated 19

Synonyms:

CT132; SPAS1; spergen1

SwissProt:

Q7Z5L4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human ovarian cancer

IHC Recommend dilution:

25-100

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兔抗SPATA19多克隆抗體

ackground:	SPATA19(spermatogenesis associated 19), also known as spergen1 (spermatogenic cell-specific gene 1 protein), CT132 or SPAS1, is a 167 amino acid mitochondrial outer membrane protein suggested to function in spermiogenesis. Expressed specifically in testis, SPATA19 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxiatelangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms’ tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
Applications:	ELISA, IHC
Name of antibody:	SPATA19
Immunogen:	Fusion protein of human SPATA19
Full name:	spermatogenesis associated 19
Synonyms:	CT132; SPAS1; spergen1
SwissProt:	Q7Z5L4
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human esophagus cancer and Human ovarian cancer
IHC Recommend dilution:	25-100