Background: |
The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. |
Applications: |
ELISA, IHC |
Name of antibody: |
SOCS7 |
Immunogen: |
Synthetic peptide of human SOCS7 |
Full name: |
suppressor of cytokine signaling 7 |
Synonyms: |
NAP4; NCKAP4 |
SwissProt: |
O14512 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer and Human ovarian cancer |
IHC Recommend dilution: |
50-200 |