IHC Recommend dilution: |
25-100 |
IHC positive control: |
Human liver cancer and Human gastric cancer |
ELISA Recommended dilution: |
1000-2000 |
SwissProt: |
Q9HCE7 |
Full name: |
SMAD specific E3 ubiquitin protein ligase 1 |
Immunogen: |
Synthetic peptide of human SMURF1 |
Name of antibody: |
SMURF1 |
Applications: |
ELISA, IHC |
Background: |
This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms. |