Background: |
The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SLC26A3 |
Immunogen: |
Fusion protein of human SLC26A3 |
Full name: |
solute carrier family 26 member 3 |
Synonyms: |
CLD; DRA |
SwissProt: |
P40879 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human cervical cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
85 kDa |
WB Positive control: |
Human hepatocellular carcinoma tissue and HepG2 cell lysates |
WB Recommended dilution: |
500-2000 |