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    • 品牌 : 通蔚生物
    • 目錄號 : TW22024
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現貨
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中文名稱:  兔抗PSMC5多克隆抗體


英文名稱:  Anti-PSMC5 rabbit polyclonal antibody


別       名:  S8; p45; SUG1; SUG-1; TBP10; TRIP1; p45/SUG; PSMC5


相關類別: 一抗


儲      存: 冷凍(-20℃) 避光


宿      主:  Rabbit


抗      原:  PSMC5


反應種屬:  Human, Mouse, Rat


標  記  物:  Unconjugate


克隆類型:  rabbit polyclonal


技術規格

Background:

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

PSMC5

Immunogen:

Fusion protein of human PSMC5

Full name:

proteasome (prosome, macropain) 26S subunit, ATPase, 5

Synonyms:

S8; p45; SUG1; SUG-1; TBP10; TRIP1; p45/SUG; PSMC5

SwissProt:

P62195

WB Predicted band size:

46 kDa

WB Positive control:

A431 and HepG2 cells

WB Recommended dilution:

500-2000




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