購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PSMB3多克隆抗體
英文名稱： Anti-PSMB3 rabbit polyclonal antibody
別 名： proteasome subunit beta 3; HC10-II
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PSMB3
反應(yīng)種屬： Human, Mouse, Rat
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
PSMB3 |
|
Immunogen: |
Fusion protein of human PSMB3 |
|
Full name: |
proteasome subunit beta 3 |
|
Synonyms: |
HC10-II |
|
SwissProt: |
P49720 |
|
ELISA Recommended dilution: |
5000-10000 |
|
IHC positive control: |
Human colorectal cancer |
|
IHC Recommend dilution: |
100-300 |
