中文名稱: 兔抗PSMB10多克隆抗體
英文名稱: Anti-PSMB10 rabbit polyclonal antibody
別 名: proteasome subunit beta 10; LMP10; MECL1; beta2i
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: PSMB10
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. |
Applications: |
ELISA, IHC |
Name of antibody: |
PSMB10 |
Immunogen: |
Fusion protein of human PSMB10 |
Full name: |
proteasome subunit beta 10 |
Synonyms: |
LMP10; MECL1; beta2i |
SwissProt: |
P40306 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human gastric cancer |
IHC Recommend dilution: |
100-300 |