中文名稱: 兔抗PRKCQ (Phospho-Ser695)多克隆抗體
英文名稱: Anti-PRKCQ (Phospho-Ser695) rabbit polyclonal antibody
別 名: PRKCT; nPKC-theta
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: PRKCQ (Phospho-Ser695)
反應(yīng)種屬: Human
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. |
Applications: |
WB, IHC |
Name of antibody: |
PRKCQ (Phospho-Ser695) |
Immunogen: |
Synthetic peptide of human PRKCQ (Phospho-Ser695) |
Full name: |
protein kinase C, theta (Phospho-Ser695) |
Synonyms: |
PRKCT; nPKC-theta |
SwissProt: |
Q04759 |
IHC positive control: |
Human lung carcinoma |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
82 kDa |
WB Positive control: |
293 cells treated with PMA |
WB Recommended dilution: |
500-1000 |