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中文名稱： 兔抗PRKAB1(Phospho-Ser181) 多克隆抗體
英文名稱： Anti-PRKAB1(Phospho-Ser181) rabbit polyclonal antibody
別 名： AMPK; HAMPKb
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： PRKAB1(Phospho-Ser181)
反應(yīng)種屬： Human Mouse Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. |
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Applications: |
WB |
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Name of antibody: |
PRKAB1(Phospho-Ser181) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 181 (L-S-S(p)-S-P) derived from Human AMPK β1. |
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Full name: |
protein kinase, AMP-activated, beta 1 non-catalytic subunit |
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Synonyms： |
AMPK; HAMPKb |
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SwissProt: |
Q9Y478 |
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WB Predicted band size: |
30 kDa |
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WB Positive control: |
Rat kidney tissue lysates |
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WB Recommended dilution: |
500-1000 |
