中文名稱: 兔抗PRKAB1(Phospho-Ser181) 多克隆抗體
英文名稱: Anti-PRKAB1(Phospho-Ser181) rabbit polyclonal antibody
別 名: AMPK; HAMPKb
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: PRKAB1(Phospho-Ser181)
反應(yīng)種屬: Human Mouse Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. |
Applications: |
WB |
Name of antibody: |
PRKAB1(Phospho-Ser181) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine 181 (L-S-S(p)-S-P) derived from Human AMPK β1. |
Full name: |
protein kinase, AMP-activated, beta 1 non-catalytic subunit |
Synonyms: |
AMPK; HAMPKb |
SwissProt: |
Q9Y478 |
WB Predicted band size: |
30 kDa |
WB Positive control: |
Rat kidney tissue lysates |
WB Recommended dilution: |
500-1000 |