中文名稱: 兔抗PLAUR多克隆抗體
英文名稱: Anti-PLAUR rabbit polyclonal antibody
別 名: CD87; UPAR; URKR; U-PAR
抗 原: PLAUR
儲 存: 冷凍(-20℃)
宿 主: Rabbit
相關類別: 一抗
反應種屬: Human
標 記 物 : Unconjugate
克隆類型: rabbit polyclonal
技術規格
Background: |
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
PLAUR |
Immunogen: |
Fusion protein of human PLAUR |
Full name: |
Plasminogen activator, urokinase receptor |
Synonyms: |
CD87; UPAR; URKR; U-PAR |
SwissProt: |
Q03405 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human lung cancer and Human colon cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
37 kDa |
WB Positive control: |
A549 cells |
WB Recommended dilution: |
500-2000 |