Background: |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. |
Applications: |
ELISA, IHC |
Name of antibody: |
GNAI3 |
Immunogen: |
Fusion protein of human GNAI3 |
Full name: |
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
Synonyms: |
87U6; ARCND1 |
SwissProt: |
P08754 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human lung cancer |
IHC Recommend dilution: |
25-100 |