Background: |
The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
GLUL |
Immunogen: |
Fusion protein of human GLUL |
Full name: |
glutamate-ammonia ligase |
Synonyms: |
GS; GLNS; PIG43; PIG59 |
SwissProt: |
P15104 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer and Human colon cancer |
IHC Recommend dilution: |
100-300 |
WB Predicted band size: |
42 kDa |
WB Positive control: |
Mouse liver and brain tissue |
WB Recommended dilution: |
500-2000 |