Background: |
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. |
Applications: |
WB, IHC, IF |
Name of antibody: |
FOXO3(Phospho-Ser253) |
Full name: |
forkhead box O3 |
Synonyms: |
FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2 |
SwissProt: |
O43524 |
IHC positive control: |
Human breast carcinoma tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
71 kDa |
WB Positive control: |
NIH/3T3 cells lysates |
WB Recommended dilution: |
500-1000 |
IF positive control: |
Hela cells |
IF Recommend dilution: |
100-200 |