中文名稱:兔抗SERPINB5多克隆抗體
英文名稱: Anti-SERPINB5 rabbit polyclonal antibody
別 名: PI5, maspin
抗 原: SERPINB5
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
相關(guān)類別: 一抗
反應(yīng)種屬: Human, Mouse
標(biāo)記物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SERPINB5 |
Immunogen: |
Fusion protein of human SERPINB5 |
Full name: |
serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
Synonyms: |
PI5, maspin |
SwissProt: |
P36952 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human esophagus cancer and human lung cancer |
IHC Recommend dilution: |
100-300 |
WB Predicted band size: |
42 kDa |
WB Positive control: |
Mouse esophagus and human cervical cancer tissue |
WB Recommended dilution: |
1000-5000 |