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021-54845833/15800441009
中文名稱：兔抗SAV1多克隆抗體
英文名稱： Anti-SAV1 rabbit polyclonal antibody
別 名： salvador family WW domain containing protein 1; SAV; WW45; WWP4
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原：SAV1
反應(yīng)種屬： Human, Mouse, Rat
標(biāo)記物： Unconjugate
克隆類型： rabbit polyclonal
Background:
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
Applications:
ELISA, WB, IHC
Name of antibody:
SAV1
Immunogen:
Fusion protein of human SAV1
Full name:
salvador family WW domain containing protein 1
Synonyms:
SAV; WW45; WWP4
SwissProt:
Q9H4B6
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human brain and Human gastric cancer
IHC Recommend dilution:
100-300
WB Predicted band size:
45 kDa
WB Positive control:
HUVEC, PC-3 cell lysates
WB Recommended dilution:
500-2000
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