中文名稱: 兔抗NFKB2(Phospho-Ser866) 多克隆抗體
英文名稱: Anti-NFKB2(Phospho-Ser866) rabbit polyclonal antibody
別 名: p52; p105; H2TF1; LYT10; CVID10; LYT-10; NF-kB2
抗 原: NFKB2(Phospho-Ser866)
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
反應種屬: Human Mouse Rat
相關類別: 一抗
標 記 物: Unconjugate
克隆類型: Unconjugate
技術規格
Background: |
NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. |
Applications: |
WB, IHC, IF |
Name of antibody: |
NFKB2(Phospho-Ser866) |
Immunogen: |
Peptide sequence around phosphorylation site of serine 866(E-D-S(p)-A-Y) derived from Human NFκB-p100/p52. |
Full name: |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
Synonyms: |
p52; p105; H2TF1; LYT10; CVID10; LYT-10; NF-kB2 |
SwissProt: |
Q00653 |
IHC positive control: |
Human breast carcinoma tissue |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
97 kDa |
WB Positive control: |
Human ovary cancer cells lysate |
WB Recommended dilution: |
500-1000 |
IF positive control: |
Hela cells |
IF Recommend dilution: |
100-200 |