購(gòu)物車(chē)
幫助
021-54845833/15800441009
英文名稱(chēng)： Anti-NFKB1 (Phospho-Ser927) rabbit polyclonal antibody
別 名： p50; KBF1; p105; EBP-1; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： NFKB1 (Phospho-Ser927)
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
NFKB1 (Phospho-Ser927) |
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Immunogen: |
Synthetic peptide of human NFKB1 (Phospho-Ser927) |
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Full name: |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (Phospho-Ser927) |
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Synonyms： |
p50; KBF1; p105; EBP-1; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B |
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SwissProt: |
P19838 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
120 kDa |
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WB Positive control: |
HL60 cells treated with TNF-α |
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WB Recommended dilution: |
500-1000 |
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IF Positive control: |
Hela cells |
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IF Recommended dilution |
100-200 |
