中文名稱: 兔抗RHOV多克隆抗體
英文名稱: Anti-RHOV rabbit polyclonal antibody
別 名: CHP; ARHV; WRCH2
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
抗 原: RHOV
宿 主: Rabbit
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. Rho V (ras homolog gene family, member V), also known as Rho GTPase-like protein ARHV, CHP or WRCH2 (Wnt-1 responsive Cdc42 homolog 2), is a 236 amino acid protein that controls the actin cytoskeleton through activation of the JNK pathway. A member of the Rho family and small GTPase superfamily, Rho V functions as a lipid anchor at the cytoplasmic side of the cell membrane and is expressed in placenta, pancreas and fetal brain. Rho V is implicated in cell transformation and is encoded by a gene located on human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
Applications: |
ELISA, IHC |
Name of antibody: |
RHOV |
Immunogen: |
Full length fusion protein |
Full name: |
ras homolog family member V |
Synonyms: |
CHP; ARHV; WRCH2 |
SwissProt: |
Q96L33 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human esophagus cancer and Human colorectal cancer |
IHC Recommend dilution: |
25-100 |