Background: |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
FOSB |
Immunogen: |
Synthetic peptide of human FOSB |
Full name: |
FBJ murine osteosarcoma viral oncogene homolog B |
Synonyms: |
AP-1; G0S3; GOS3; GOSB |
SwissProt: |
P53539 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer and Human thyroid cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
36 kDa |
WB Positive control: |
Human kidney cancer and lung cancer tissue, human placenta tissue |
WB Recommended dilution: |
200-1000 |