Background:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]
Applications:
WB, IHC
Name of antibody:
FOS(Phospho-Thr232)
Immunogen:
Peptide sequence around phosphorylation site of threonine 232(V-A-T(p)-P-E) derived from Human FOS .
Full name:
FBJ murine osteosarcoma viral oncogene homolog
Synonyms:
p55; AP-1; C-FOS
SwissProt:
P01100
IHC positive control:
Human breast carcinoma tissue
IHC Recommend dilution:
50-100
WB Predicted band size:
41 kDa
WB Positive control:
COS7 cells lysates
WB Recommended dilution:
500-1000