Background: |
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. |
Applications: |
ELISA, IHC |
Name of antibody: |
FASN |
Immunogen: |
Synthetic peptide of human FASN |
Full name: |
fatty acid synthase |
Synonyms: |
FAS; OA-519; SDR27X1 |
SwissProt: |
P49327 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human breast cancer |
IHC Recommend dilution: |
25-100 |