Background:
This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Applications:
ELISA, IHC
Name of antibody:
FAN1
Immunogen:
Synthetic peptide of human FAN1
Full name:
FANCD2 and FANCI associated nuclease 1
Synonyms:
KMIN; hFAN1; MTMR15; KIAA1018
SwissProt:
Q9Y2M0
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human lung cancer and Human ovarian cancer
IHC Recommend dilution:
30-150