中文名稱：兔抗FADD多克隆抗體

英文名稱： Anti-FADD rabbit polyclonal antibody

別名： GIG3, MORT1

抗原： FADD

儲存： 冷凍（-20℃）

宿主： Rabbit

相關類別： 一抗

反應種屬： Human

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術規(guī)格

Background:

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.

Applications:

ELISA, IHC

Name of antibody:

FADD

Immunogen:

Fusion protein of human FADD

Full name:

Fas (TNFRSF6)-associated via death domain

Synonyms：

GIG3, MORT1

SwissProt:

Q13158

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and Human esophagus cancer

IHC Recommend dilution:

50-150

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兔抗FADD多克隆抗體

Background:	The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Applications:	ELISA, IHC
Name of antibody:	FADD
Immunogen:	Fusion protein of human FADD
Full name:	Fas (TNFRSF6)-associated via death domain
Synonyms：	GIG3, MORT1
SwissProt:	Q13158
ELISA Recommended dilution:	1000-5000
IHC positive control:	Human thyroid cancer and Human esophagus cancer
IHC Recommend dilution:	50-150