中文名稱:兔抗RGS1多克隆抗體
英文名稱: Anti-RGS1 rabbit polyclonal antibody
別 名: 1R20; BL34; IER1; IR20; HEL-S-87
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: RGS1
反應(yīng)種屬: Human, Mouse
標(biāo)記物: Unconjugate
克隆類型: rabbit polyclonal
Background:
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Applications:
ELISA, WB, IHC
Name of antibody:
RGS1
Immunogen:
Fusion protein of human RGS1
Full name:
regulator of G-protein signaling 1
Synonyms:
1R20; BL34; IER1; IR20; HEL-S-87
SwissProt:
Q08116
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human prostate cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
24 kDa
WB Positive control:
RAW264.7 cells
WB Recommended dilution:
500-2000
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