Background: |
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. |
Applications: |
WB |
Name of antibody: |
ETV6 |
Immunogen: |
Fusion protein of human ETV6 |
Full name: |
ets variant 6 |
Synonyms: |
TEL; TEL/ABL |
SwissProt: |
P41212 |
WB Predicted band size: |
53 kDa |
WB Positive control: |
A431 cells |
WB Recommended dilution: |
500-2000 |