Background: |
This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. |
Applications: |
WB |
Name of antibody: |
ETV1 |
Immunogen: |
Synthesized peptide derived from N-terminal of human ER81. |
Full name: |
ets variant 1 |
Synonyms: |
ER81 |
SwissProt: |
P50549 |
WB Predicted band size: |
55 kDa |
WB Positive control: |
Huvec cells lysates treated with PMA (125ng/ml, 30mins) |
WB Recommended dilution: |
500-3000 |