英文名稱: TSC22D1 Antigen (Recombinant Protein)
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述
Full name: |
TSC22 domain family, member 1 |
Synonyms: |
Ptg-2; TSC22; TGFB1I4 |
Swissprot: |
Q15714 |
Gene Accession: |
BC000456 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |