中文名稱:兔抗RAF1(Phospho-Ser296) 多克隆抗體
英文名稱: Anti-RAF1(Phospho-Ser296) rabbit polyclonal antibody
別 名: NS5; CRAF; Raf-1; c-Raf; CMD1NN
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
反應種屬: Human Mouse Rat
標記物: Unconjugate
克隆類型: Unconjugate
技術規格
Background: |
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. |
Applications: |
WB |
Name of antibody: |
RAF1(Phospho-Ser296) |
Immunogen: |
Peptide sequence around phosphorylation site of serine 296 (S-S-S(p)-P-N) derived from Human C-RAF. |
Full name: |
Raf-1 proto-oncogene, serine/threonine kinase |
Synonyms: |
NS5; CRAF; Raf-1; c-Raf; CMD1NN |
SwissProt: |
P04049 |
WB Predicted band size: |
73 kDa |
WB Positive control: |
293 cells lysates treated with PMA |
WB Recommended dilution: |
500-1000 |