Background: |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. |
Applications: |
ELISA, IHC |
Name of antibody: |
EPHA1 |
Immunogen: |
Synthetic peptide of human EPHA1 |
Full name: |
Ephrin type-A receptor 1 |
Synonyms: |
EPH, EPHT, EPHT1 |
SwissProt: |
P21709 |
ELISA Recommended dilution: |
500-5000 |
IHC positive control: |
Human colon cancer |
IHC Recommend dilution: |
10-50 |