購物車
幫助
021-54845833/15800441009
中文名稱： PCNA抗原（重組蛋白）
英文名稱： PCNA Antigen (Recombinant Protein)
儲 存： 冷凍（-20℃）
相關類別： 抗原
概 述
|
Full name: |
Proliferating cell nuclear antigen |
|
Synonyms: |
ATLD2 |
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Swissprot: |
P12004 |
|
Gene Accession: |
BC000491 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome |
