中文名稱: PSMB4 抗原(重組蛋白)
英文名稱: PSMB4 Antigen (Recombinant Protein)
別 名: proteasome subunit beta 4; HN3; HsN3; PROS26; PROS-26
概 述
Full name: |
proteasome subunit beta 4 |
Synonyms: |
HN3; HsN3; PROS26; PROS-26 |
Swissprot: |
P28070 |
Gene Accession: |
BC017307 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. |