概 述
Full name: |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa |
Synonyms: |
B12; CI-B12 |
Swissprot: |
O43676 |
Gene Accession: |
BC018183 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. |