中文名稱:兔抗PTPRK多克隆抗體
英文名稱: Anti-PTPRK rabbit polyclonal antibody
別 名: R-PTP-kappa
抗 原: PTPRK
儲 存: 冷凍(-20℃)
宿 主: Rabbit
相關類別: 一抗
反應種屬: Human
標記物: Unconjugate
克隆類型: rabbit polyclonal
技術規格
Background: |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. |
Applications: |
ELISA, IHC |
Name of antibody: |
PTPRK |
Immunogen: |
Fusion protein of human PTPRK |
Full name: |
protein tyrosine phosphatase, receptor type, K |
Synonyms: |
R-PTP-kappa |
SwissProt: |
Q6P493 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human liver cancer and Human ovarian cancer |
IHC Recommend dilution: |
25-100 |