Background: |
The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
ELP1 |
Immunogen: |
Synthetic peptide of human ELP1 |
Full name: |
elongator complex protein 1 |
Synonyms: |
FD; DYS; IKAP; IKI3; TOT1; IKBKAP |
SwissProt: |
O95163 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
150 kDa |
WB Positive control: |
231, K562 and A172 cell lysates |
WB Recommended dilution: |
200-1000 |