Background: |
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. |
Applications: |
IHC, IF |
Name of antibody: |
ELK1(Phospho-Thr417) |
Immunogen: |
Peptide sequence around phosphorylation site of threonine 417(L-S-T(p)-P-V) derived from Human Elk1. |
Full name: |
ELK1, member of ETS oncogene family |
Synonyms: |
0 |
SwissProt: |
P19419 |
IHC positive control: |
Human breast carcinoma tissue |
IHC Recommend dilution: |
50-100 |
IF positive control: |
Hela cells |
IF Recommend dilution: |
100-200 |