Background: |
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
ELAVL1 |
Immunogen: |
Fusion protein of human ELAVL1 |
Full name: |
ELAV like RNA binding protein 1 |
Synonyms: |
HUR; Hua; MelG; ELAV1 |
SwissProt: |
Q15717 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human lung cancer and human brain |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
36 kDa |
WB Positive control: |
293T, A431, NIH/3T3, hela and hepG2 cells |
WB Recommended dilution: |
500-2000 |