Background: |
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
EIF2B3 |
Immunogen: |
Fusion protein of human EIF2B3 |
Full name: |
eukaryotic translation initiation factor 2B subunit gamma |
Synonyms: |
EIF-2B; EIF2Bgamma |
SwissProt: |
Q9NR50 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer and Human esophagus cancer |
IHC Recommend dilution: |
100-200 |