中文名稱(chēng)：兔抗EID1多克隆抗體

英文名稱(chēng)： Anti-EID1 rabbit polyclonal antibody

別名： CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620

相關(guān)類(lèi)別： 一抗

儲(chǔ) 存： 冷凍（-20℃）

抗原： EID1

宿主： Rabbit

反應(yīng)種屬： Human, Mouse

標(biāo) 記物： Unconjugate

克隆類(lèi)型： rabbit polyclonal

技術(shù)規(guī)格

Background:

E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.

Applications:

ELISA, WB, IHC

Name of antibody:

EID1

Immunogen:

Fusion protein of human EID1

Full name:

EP300 interacting inhibitor of differentiation 1

Synonyms：

CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620

SwissProt:

Q9Y6B2

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human colon cancer and human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

21 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

200-1000

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兔抗EID1多克隆抗體

Background:	E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
Applications:	ELISA, WB, IHC
Name of antibody:	EID1
Immunogen:	Fusion protein of human EID1
Full name:	EP300 interacting inhibitor of differentiation 1
Synonyms：	CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620
SwissProt:	Q9Y6B2
ELISA Recommended dilution:	1000-2000
IHC positive control:	Human colon cancer and human esophagus cancer
IHC Recommend dilution:	25-100
WB Predicted band size:	21 kDa
WB Positive control:	Mouse heart tissue
WB Recommended dilution:	200-1000