Background: |
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. |
Applications: |
WB |
Name of antibody: |
EGFR(Phospho-Ser1071) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine 1071 (Y-S-S(p)-D-P) derived from Human EGFR. |
Full name: |
epidermal growth factor receptor |
Synonyms: |
ERBB; HER1; mENA; ERBB1; PIG61 |
SwissProt: |
P00533 |
WB Predicted band size: |
134 kDa |
WB Positive control: |
Rat renin lysates |
WB Recommended dilution: |
500-1000 |