Background: |
This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
ECM1 |
Immunogen: |
Synthetic peptide of human ECM1 |
Full name: |
extracellular matrix protein 1 |
Synonyms: |
URBWD |
SwissProt: |
Q16610 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human breast cancer |
IHC Recommend dilution: |
50-100 |
WB Predicted band size: |
61 kDa |
WB Positive control: |
MCF7 cell lysate |
WB Recommended dilution: |
500-2000 |