Background: |
This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
DUS2 |
Immunogen: |
Fusion protein of human DUS2 |
Full name: |
dihydrouridine synthase 2 |
Synonyms: |
SMM1; DUS2L; URLC8 |
SwissProt: |
Q9NX74 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human thyroid cancer |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
55 kDa |
WB Positive control: |
HepG2 cell and Human Bladder transitional cell carcinoma grade 2-3 tissue lysates |
WB Recommended dilution: |
200-1000 |