中文名稱：兔抗DSP多克隆抗體

英文名稱： Anti-DSP rabbit polyclonal antibody

別名： DP; DPI; DPII

相關類別： 一抗

儲存： 冷凍（-20℃）

宿主： Rabbit

抗原： DSP

反應種屬： Human, Mouse

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術規(guī)格

Background:

Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.

Applications:

ELISA, IHC

Name of antibody:

DSP

Immunogen:

Synthetic peptide of human DSP

Full name:

desmoplakin

Synonyms：

DP; DPI; DPII

SwissProt:

P15924

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human breast cancer and Human brain

IHC Recommend dilution:

25-100

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兔抗DSP多克隆抗體

Background:	Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
Applications:	ELISA, IHC
Name of antibody:	DSP
Immunogen:	Synthetic peptide of human DSP
Full name:	desmoplakin
Synonyms：	DP; DPI; DPII
SwissProt:	P15924
ELISA Recommended dilution:	1000-2000
IHC positive control:	Human breast cancer and Human brain
IHC Recommend dilution:	25-100