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中文名稱： 兔抗MICA多克隆抗體
英文名稱： Anti-MICA rabbit polyclonal antibody
別 名： MHC class I polypeptide-related sequence A; MIC-A; PERB11.1
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： MICA
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MICA |
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Immunogen: |
Fusion protein of human MICA |
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Full name: |
MHC class I polypeptide-related sequence A |
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Synonyms: |
MIC-A; PERB11.1 |
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SwissProt: |
Q29983 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
50-200 |
