Background: |
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. |
Applications: |
ELISA, IHC |
Name of antibody: |
DRD2 |
Immunogen: |
Synthetic peptide of human DRD2 |
Full name: |
dopamine receptor D2 |
Synonyms: |
D2R; D2DR |
SwissProt: |
P14416 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human breast cancer |
IHC Recommend dilution: |
25-100 |